Duloxetine and Amitriptyline Reduce Neuropathic Pain by Inhibiting Primary Sensory Input to Spinal Dorsal Horn Neurons via α1-and α2-Adrenergic Receptors

Y Huang, H Chen, SR Chen… - ACS Chemical …, 2023 - ACS Publications
… concentrations of norepinephrine. The α1- and α2-adrenergic receptor agonists inhibit
glutamatergic … (n = 10 rats per group), we intrathecally injected 50 μg of WB-4101 20 min before ip …